Research Teams & Labs
Congestive heart failure is a major public health problem, afflicting millions of Americans and costing our health care system in excess of $30 billion annually. Heart failure is also incredibly morbid, with a 5-year mortality of ~50%, which is worse than most common forms of cancer. Our lab uses all means of molecular and genetic tools to study the fundamental processes in the heart that underlie cardiac dysfunction and failure. A major focus of the lab is characterizing the epigenomic changes that occur in heart failure. Our mission is to translate this research into clinical advances that will have a meaningful impact on patient care.
Emory Cardiovascular Imaging & Biomechanics Core Laboratory
The Davis basic science cardiovascular laboratory focuses on various aspects of cardiac regeneration and preservation using molecular-based and biomaterials-based approaches to restoring function after cardiac injury.
The mission of the Emory Clinical Cardiovascular Research Institute (ECCRI) is to better understand the pathophysiology of cardiovascular disease and to develop new approaches to the manipulation of cardiovascular function and the treatment of disease.
The Griendling basic science cardiology laboratory focuses on the role of reactive oxygen species in smooth muscle proliferation, migration and differentiation, and the role of oxidative stress in the pathogenesis of vascular disease.
Jo Lab in Vascular Mechanobiology and Disease
Cardiovascular diseases are the leading causes of death and disability worldwide. We are dedicated to developing new therapies to help cardiac patients by identifying, testing, and moving new therapies towards clinical use. We study stem cell therapies to prevent heart damage and promoting repair. We use biomaterials to increase cell retention, increase efficacy, and target activity.
The Lyle basic science cardiovascular lab focuses on how vascular inflammation modulates new blood vessel formation and vascular disease pathogenesis, as well as the use of stem cells as a new approach to the delivery of therapeutics to ischemic tissues.
The Microscopy in Medicine Core at Emory University was established in 2000 as a core facility providing access to histology and state-of-the-art imaging instrumentation on a shared-use basis to faculty, staff and students of the Emory Division of Cardiology and Emory Department of Medicine. The facility is located in the Woodruff Memorial Research Building (WMB) on the Emory campus.
The Rezvan lab focuses on how mechanical forces influence the interaction between endothelial cells and the immune system, contributing to atherosclerotic cardiovascular diseases
The focus of the San Martin research is on understanding smooth muscle cell (VSMC) signaling pathways and phenotypic modulation during normal physiological conditions and during diseases. We are particularly interested in the participation of reactive oxygen species (ROS) produced by the NADPH oxidase (Nox) family of enzymes as mediators of a wider repertoire of cellular responses such as: cytoskeleton reorganization and gene expression.
The Searles cardiovascular lab is focused on molecular mechanisms by which different physiologic and pathophysiologic stimuli modulate vascular gene expression.
The overall focus of the Taylor laboratory is to gain a better understanding of the role of inflammation in cardiovascular disease.
The Yoon Lab has been working on stem cell research in various cardiovascular diseases. Our major research interest is to use stem cell technology to treat various cardiovascular diseases, and we have been developing and using different bone marrow-derived stem sell or progenitor cells for cardiovascular repair.