Biorepositories

The biorepositories outlined on this page are a Emory campus-wide collection of biorepositories.

Brain and Tissue Bank


Principal Investigator Marla Gearing
Contact Person Marla Gearing, mgearin@emory.edu, (404)712-8352
Division/Organization Neuropathology Histochemistry @ Emory NINDS
Types of Samples Frozen and fixed autopsy brain tissues from patients with neurodegenerative diseases
Phenotypic/Genotypic Data Available

Samples are associated with well-characterized patients with dementia, movement disorders, sleep disorders, stroke, neuromuscular disorders and other nervous system diseases as well as healthy control subjects.

Interest in Collaboration
More Information
  • The Neuropathology/Histochemistry Core, located in the Center for Neurodegenerative Disease (CND) on the 5th floor of the Whitehead Research Building, provides brain tissue processing and staining services and neuropathological analysis for investigators who do not have the necessary resources or expertise.
  • These resources are available to NINDS funded researchers and other researchers upon request.
  • Requests must be approved by the CND Tissue Committee prior to distribution of human brain tissues and other materials.
  • Charges reflect only the cost of distributing samples; there is no charge for the samples themselves.

CDC Biorepository(CBR)


Principal Investigator Geraldine McQuillan
Contact Person Geraldine McQuillan,Gmm2@cdc.gov,301-458-4371 
Division/Organization CDC NHANES (National Health and Nutrition Examination Survey)
Types of Samples Serum samples
Phenotypic/Genotypic Data Available Linked to samples can be viewed at  http://www.cdc.gov/nchs/nhanes/nhanes_questionnaires.htm 
Includes demographic, socioeconomic, dietary, and health-related data, medical, dental and physiological measurements; lab tests
Genetic data can be obtained from Jody Mclean, Ica8@cdc.gov, 301-458-4102
Interest in Collaboration Yes
More Information CASPIR is the main CDC repository with over 2 million specimen vials almost all in liquid nitrogen. Almost all Centers use this repository and NHANES is just a collection in CASPIR. We have mostly sera 6-7 vials per sample person, but also 1 vial of plasma and 1 vial of urine per sample person.

 

CHOA-CAYACSS

Principal Investigator

Karen Wasilewski-Masker, MD, M.S.C.R

Contact Person

Amanda Sanders, 404-785-0305

Division/Organization CHOA/AFLAC
Types of Samples Non-Analyzed Extracted DNA
Phenotypic/Genotypic Data Available Demographics, cancer diagnosis, detailed treatment history (surgery, radiation, chemotherapy, other biologic agents), medical problems including long term effects of cancer therapy
Interest in Collaboration Yes
More Information
  • The purpose of this study is to learn more about health problems that may develop in patient survivors and potential barriers to health care.
  • CHOA-CAYACSS includes patients who were diagnosed with cancer or received cancer like treatment under the age of 30. This study includes patient survivors that have recently been diagnosed to those who have been off therapy for a number of years. Samples in this repository are from patients meeting the aforementioned criteria who have agreed to participate in the CHOA-CAYACSS study.

 

Cocaine Use


Principal Investigator Erica Duncan
Contact Person

Erica Duncan, Erica.duncan@va.gov, 404-321-6111 ext 7532

Division/Organization SOM
Types of Samples
Phenotypic/Genotypic Data Available Phenotypic, limited genotypic
Interest in Collaboration Yes
More Information Samples were collected from cocaine users and healthy controls.

 

Cystic Fibrosis (CF) Biospecimen

Principal Investigator Arlene Stecenko, MD
Contact Person

Julie Flores, jkozars@emory.edu, (404)727-1968

Division/Organization Pediatrics/Pulmonary, Allergy/Immunology, Cystic Fibrosis, and Sleep
Types of Samples Blood, sputum (expectorated and induced), airway fluids (EBC, BAL), nasal cells, bacterial isolates
Phenotypic/Genotypic Data Available Clinical data available
Interest in Collaboration Yes
More Information The CF Biospecimen Repository is a storage bank of several thousand biofluids collected from patients with cystic fibrosis at varying disease states. Patients are consented from both the adult and pediatric clinics at Emory and may donate samples at outpatient clinic visits or when hospitalized. We believe that these treasured samples may be the keys that will allow our researchers to unlock the mysteries underlying the changes that occur in the lungs of CF patients as the disease progresses.

Explanted Hearts

Principal Investigator W. Robert Taylor, MD
Contact Person

W. Robert Taylor, WTAYLOR@emory.edu, (404)727-8921

Division/Organization Cardiology
Types of Samples Myocardium and coronaries from explanted hearts.  Frozen sections, paraffin sections and some protein and RNA samples
Phenotypic/Genotypic Data Available Not available.  Patients de-identified.
Interest in Collaboration Yes
More Information Explanted hearts from the last 10 years

HIV Specimen Repository of the Center for AIDS Research

Principal Investigator Colleen Kelley
Contact Person

Cameron England, c.v.england@emory.edu, (404) 616-9330

Division/Organization CFAR Clinical Research Core
Types of Samples

Blood products including PBMCs, plasma and sera

Phenotypic/Genotypic Data Available Standard data collected are demographic, viral load, CD4, ARV treatment regimen; and also have IRB approval to access patient medical records for additional data.
Interest in Collaboration Yes
More Information

 Repository of common and rare HIV cases including patients on ART, elite controllers, long-term non-progressors, and acute HIV infection.  Special requests can be made for rectal tissue, leukapheresis and other cases not in the repository.

 

Ketosis Prone Diabetes Mellitus (KPDM) in African American; Insulin Signaling, Proteonomics and Genomics

Principal Investigator Dr. Priyathama Vellanki
Contact Person

Dr. Omolade Oladejo

Division/Organization Endocrinology
Types of Samples Serum aliquots from the modified oral glucose tolerance test (-5min - 120min), muscle biopsies
Phenotypic/Genotypic Data Available

African American patients, BMI more than 28, between 18-65 years.

Interest in Collaboration Yes
More Information

Samples are from 34 patients enrolled in the KPDM study who are active.  Muscle biopsy samples collected one week after the onset of KPDM (Acute Hyperglycemia or DKA) and one week after weaning off insulin (takes around 8-12 weeks the weaning off process).  At that moment patients receive a modified oral glucose tolerance test (mOGTT), which is repeated after 3 months, and then every 6 months until a total of 7 mOGTTs are collected.  Samples are stored in GCRC-Grady freezers.

 

Predictive Health Institute Center for Health Discovery and Well Being Cohort

Principal Investigator Greg Martin, MD
Contact Person

Jane Clark, jbclark@emory.edu, (404) 727-3845

Division/Organization [predictivehealth.emory.edu]Predictive Health Institute Center for Health Discovery and Well Being, Georgia CTSA
Types of Samples

Predictive Health Institute Data/Sample request

Phenotypic/Genotypic Data Available Predictive Health Institute Data/Sample request
Interest in Collaboration Yes

 

Schizophrenia

Principal Investigator Erica Duncan
Contact Person

Erica Duncan, Erica.duncan@va.gov, (404) 321-6111 ext 7532

Division/Organization SOM
Types of Samples
Phenotypic/Genotypic Data Available Phenotypic, limited genotypic 
Interest in Collaboration Yes
More Information

 

Sepsis/ARDS Registry

Principal Investigator Greg Martin
Contact Person Leona.wells@emory.edu, (404) 251-1650
Division/Organization SOM/Pulmonary and Critical Care
Types of Samples Urine, whole blood, plasma, and serum collected within the first 72 hours of developing sepsis or ARDS. 
Phenotypic/Genotypic Data Available Demographics, information during index hospitalization with disease including physiological and laboratory parameters and clinical outcomes (length of hospital stay, vital status at discharge)
Interest in Collaboration Yes
More Information Prospective registry of sepsis and acute respiratory distress syndrome patients in the Emory system and affiliates, which serves as a foundation for subsequent enrollment into clinical trials.

Transplant Center Biorepository

Principal Investigator Aneesh Mehta, MD
Contact Person

Jennifer Robertson, jennifer.robertson@emory.edu, (404)727-2017 or Annette Hadley, ahadley@emory.edu, (404)727-8355

Division/Organization Emory Transplant Center
Types of Samples Blood, urine, tissue samples from solid organ transplant recipients and/or patients with end-stage organ disease who are awaiting organ transplant; blood and urine from living kidney donors and healthy controls. Now includes pediatric samples as well.
Phenotypic/Genotypic Data Available Renal diagnoses of rejection, stable function or viremia.
Interest in Collaboration Yes
More Information

Click here for detailed description

RedCap data base in place in which kidney biopsies tracked.  The clinical data from the biopsies are uploaded in RedCap and reviewed by a nephrologists to make a diagnosis which is then associated to the sample set.  

Study Request Form https://redcap.emory.edu/surveys/?s=DYXETPXFHY
Specimen Request Form https://redcap.emory.edu/surveys/?s=DYXETPXFHY