Biorepositories

The biorepositories outlined on this page are a Emory campus-wide collection of biorepositories.

Abnormalities in B-cell Function and Signal Transduction in SLE

Principal Investigator Ignacio Sanz
Contact Person In addition to PI, please contact Jennifer Scantlin atjennifer.scantlin@emory.edu or 404-712-2943 
Division/Organization Rheumatology/Lowance Center
Types of Samples, Phenotypic/Genotypic Data Available Tonsil Samples
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to emory under approved MTAs.

Autoimmunity Patient Cohort

Principal Investigator Ignacio Sanz
Contact Person In addition to PI, please contact Jennifer Scantlin atjennifer.scantlin@emory.edu or 404-712-2943 
Division/Organization Rheumatology/Lowance Center
Types of Samples, Phenotypic/Genotypic Data Available Serum Samples
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to emory under approved MTAs.

 

B cell gene expression in SLE

Principal Investigator Ignacio Sanz
Contact Person In addition to PI, please contact Jennifer Scantlin atjennifer.scantlin@emory.edu or 404-712-2943 
Division/Organization Rheumatology/Lowance Center
Types of Samples Blood Samples
Phenotypic/Genotypic Data Available Gene expression profiles from different B cell subsets by microarray.
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to emory under approved MTAs.

 

B Cell Tolerance Mechanisms in Human SLE


Principal Investigator Ignacio Sanz
Contact Person In addition to PI, please call Jennifer Scantlin- 404-712-2943- jennifer.scantlin@emory.edu
Division/Organization Rheumatology/Lowance Center
Types of Samples Blood, bone marrow
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to emory under approved MTAs.

Brain and Tissue Bank


Principal Investigator Marla Gearing
Contact Person Nancy Ciliax, nciliax@emory.edu, 404-727-4927
Division/Organization Neuropathology Histochemistry @ Emory NINDS
Types of Samples Frozen tissues, brain biopsies, formalin- and paraformaldehyde-fixed tissues, plasma samples, buffy coat isolates, DNA extracts, CSF
Phenotypic/Genotypic Data Available

Samples are associated with well-characterized patients with dementia, movement disorders, sleep disorders, stroke, neuromuscular disorders and other nervous system diseases as well as healthy control subjects.

Interest in Collaboration
More Information
  • The Neuropathology/Histochemistry Core, located in the Center for Neurodegenerative Disease (CND) on the 5th floor of the Whitehead Research Building, provides brain tissue processing and staining services and neuropathological analysis for investigators who do not have the necessary resources or expertise.
  • These resources are available to NINDS funded researchers and other researchers upon request.
  • Requests must be approved by the CND Tissue Committee prior to distribution of human brain tissues and other materials.
  • Charges reflect only the cost of distributing samples; there is no charge for the samples themselves.

Cardiovascular Biobank

Principal Investigator Arshed Quyyumi
Division/Organization Cardiology
Types of Samples Plasma, serum, DNA, RNA
Phenotypic/Genotypic Data Available PHI, questionnaires, follow-up for adverse cardiovascular events, death.  Some genotyping, gene expression data.
Interest in Collaboration
More Information Repository of patients undergoing cardiac catheterization. Metabolomic data planned.

 

CASPIR


Principal Investigator Geraldine McQuillan
Contact Person Geraldine McQuillan, Ph.D., Gmm2@cdc.gov, 301-458-4371 
Division/Organization CDC NHANES (National Health and Nutrition Examination Survey)
Types of Samples Serum samples
Phenotypic/Genotypic Data Available Linked to samples can be viewed at http://www.cdc.gov/nchs/nhanes/nhanes_questionnaires.htm 
Includes demographic, socioeconomic, dietary, and health-related data, medical, dental and physiological measurements; lab tests
Genetic data can be obtained from Jody Mclean, Ica8@cdc.gov, 301-458-4102
Interest in Collaboration Yes
More Information
  • CASPIR is the main CDC repository with over 2 million specimen vials almost all in liquid nitrogen. 
  • Almost all Centers use this repository and NHANES is just a collection in CASPIR. 
  • We have mostly sera 6-7 vials per sample person, but also 1 vial of plasma and 1 vial of urine per sample person.

 

CHOA-CAYACSS

Principal Investigator

Karen Wasilewski-Masker, MD, M.S.C.R

Contact Person

Kristen Vangile, MPH, 404-785-7758, Kristen.Vangile@choa.org 

Division/Organization CHOA/AFLAC
Types of Samples Non-Analyzed Extracted DNA
Phenotypic/Genotypic Data Available Demographics, cancer diagnosis, detailed treatment history (surgery, radiation, chemotherapy, other biologic agents), medical problems including long term effects of cancer therapy
Interest in Collaboration Yes
More Information
  • The purpose of this study is to learn more about health problems that may develop in patient survivors and potential barriers to health care.
  • CHOA-CAYACSS includes patients who were diagnosed with cancer or received cancer like treatment under the age of 30. This study includes patient survivors that have recently been diagnosed to those who have been off therapy for a number of years. Samples in this repository are from patients meeting the aforementioned criteria who have agreed to participate in the CHOA-CAYACSS study.

 

Cocaine Use


Principal Investigator Erica Duncan
Contact Person

Erica Duncan, MD, 404-321-6111 ext 7532,Erica.duncan@va.gov

Division/Organization Psychiatry
Types of Samples Frozen whole blood, extracted DNA
Phenotypic/Genotypic Data Available Results of structured diagnostic interviews, demographic information, smoking status questionnaire, substance abuse history, symptom ratings, results of acoustic startle testing, results of reward paradigm.
Interest in Collaboration Yes
More Information Samples were collected from cocaine users and healthy controls.

 

Clinical Research in Genetics (CRIG)

Principal Investigator
Drs. Steve Warren and Lisa Kobrynski
Contact Person
Karlene Coleman, RN, MN, CGC; 404-785-6641;Karlene.coleman@choa.org
Types of Samples
DNA and serum
Associated Phenotypic / Genotypic Data
We have a database in RedCap at Emory that collects cardiology, immunology, endocrinology and psychological testing data on the patients with the 22q11.2 deletion syndrome.
Interest in Collaboration
Yes
More Information
The purpose of this study is to help researchers understand if particular physical and/or health characteristics (called "phenotypes") are caused by particular changes in a person's genes. Many researchers in the Department of Human Genetics store samples on a variety of genetic diagnoses in this repository.  My group specifically stores DNA on individuals with the 22q11.2 deletion syndrome.

CRIN (Clinical Research in Neurology)

Principal Investigator Allan Levey
Contact Person

Allan Levey, MD, PhD, alevey@emory.edu

Division/Organization Neurology
Types of Samples Blood, DNA, lymphoblasts, spinal fluid
Phenotypic/Genotypic Data Available Clinical phenotyping that includes diagnosis, family history, MMSE is available on most subjects.
Interest in Collaboration Yes
More Information A registry of Emory Neurology patients with varied conditions, including cognitive, neuromuscular, movement, vascular, and other disorders, as well as community control subjects, who have all agreed to make their medical records available for research and in many cases blood and DNA samples.

 

Children's Center for Transplantation and Immune-mediated Disorders - CTID

Principal Investigator Allan Kirk and Subra Kugathasan
Contact Person In addition to PI, please contact Jennifer Cheeseman - 404-727-8595- jcheese@emory.edu
Division/Organization Center for Transplantation and Immune-Mediated Disorders (CTID)
Types of Samples PBMCs, plasma, whole blood, DNA, urine from pediatric patients with immune-mediated disorders, solid organ transplant recipients and/or patients with end-stage organ disease who are awaiting organ transplant; blood and urine from living kidney donors and healthy controls. Renal diagnoses of rejection, stable function or viremia available for biopsies and associated samples. Clinical data can be made available upon request.
Interest in Collaboration Yes
Study Request Form http://survey.emory.edu/fs-etcbiostudyrequest.aspx
Specimen Request Form http://survey.emory.edu/fs-etcbiospecirequest.aspx

 

Cystic Fibrosis (CF) Biospecimen

Principal Investigator Arlene Stecenko, MD
Contact Person

Jane Wei, wwei@emory.edu 

Division/Organization Pediatrics
Types of Samples Adult subjects:  Blood, sputum, and exhaled breath condensate; pediatric subjects:  Blood, sputum (if available) or nasopharyngeal swab (if sputum cannot be produced); we also maintain a collection of bacterial isolates from sputum samples, most of which are tied to clinical data.
Phenotypic/Genotypic Data Available Full clinical data on each subject providing samples, including CFTR genotype (if known)
Interest in Collaboration Yes
More Information

View the most up to date information on the Core's website: http://www.pedsresearch.org/research/cores/cf-discovery-core/overview/

Executive Health Discovery Database & Biobank

Principal Investigator David Roberts
Contact Person

David Roberts, MD, drobe04@emory.edu, 404-778-1234

Division/Organization General Medicine & Geriatrics
Types of Samples Red Top (Serum), Lavender (EDTA), Green Top (Heparin), PAX (DNA and RNA), Urine (Proteomics), Post Exercise Lavender ( Lipid Associated Oxidation)
Phenotypic/Genotypic Data Available Comprehensive history & physical, family and social history, habits – alcohol, exercise, tobacco, travel, electrocardiogram (EKG), chest x-ray every 2 years, treadmill stress testing every 2 years, cardiac CT scoring every 5 years, mammogram, pap smear with HPV, bone density, laboratory data (CBC, lipids, hs-CRP, hepatic/renal biochemical profiles, TSH, urinalysis, uric acid, ferritin, Vit D, Vit B12, PSA, HGB A1C, urine albumin), colonoscopy if >50, cardiovascular diagnostic studies: nuclear, echo, stress, carotid and aortic ultrasounds, CT lung if smoker
Interest in Collaboration Yes
More Information
  • Translation of new ideas and technologies to humans for detection of disease and maintenance of health
  • Cardiovascular Health and Disease:
    • Biomarker Identification
    • Novel Biomarker Assays
    • Genetics, microRNA, etc.
  • Cancer biomarkers or Genetics
  • Alzheimer’s, Degenerative Neurologic disorders
  • Open for possible new ideas and projects    

Samples stored at ACTSI tracked by LIMS.
Database/samples available January 2012. 


Consent for research participation and longitudinal blood/urine samples from all patients in Executive Health; 1205 physicals during 2011, 91% between ages 40- 70, 80% male, 20% female

Explanted Hearts

Principal Investigator W. Robert Taylor, MD
Contact Person

W. Robert Taylor, MD; 404-727-8921; WTAYLOR@emory.edu

Division/Organization Cardiology
Types of Samples Myocardium and coronaries from explanted hearts.  Frozen sections, paraffin sections and some protein and RNA samples
Phenotypic/Genotypic Data Available Not available.  Patients de-identified.
Interest in Collaboration Yes
More Information Explanted hearts from the last 10 years

FFA-induced Hypertension and Endothelial Dysfunction in Obese Subjects

Principal Investigator Guillermo Umpierrez
Contact Person

Gonzalo Robalino; (404) 616 3719; garobal@emory.edu

Division/Organization Endocrinology
Types of Samples

Serum and plasma samples from obese non diabetics without hypertension

Phenotypic/Genotypic Data Available Obese non diabetic volunteers without hypertension who were admitted to the Grady CIN to undergo intralipid 20% infusions, normal saline infusions, a low fat oral load and a high fat oral load.  Blood pressure and inflammatory responses.
Interest in Collaboration Yes
More Information

Samples are from 13 obese non diabetics without hypertension who received; 8 hour intralipid 20% infusions at a rate of 20 and 40 ml/hour (10 serum samples  and 10 plasma samples per patient per admission); an 8 hour normal saline infusion (10 serum samples  and 10 plasma samples per patient per admission); a low fat oral load and a high fat oral load (10 serum samples 10 plasma samples per patient per admission); a total of 5 admissions per subject on different dates.

 

Free Fatty Acid-Induced Hypertension in Obese Subjects with Type 2 Diabetes

Principal Investigator Guillermo Umpierrez
Contact Person

Gonzalo Robalino; (404) 616 3719; garobal@emory.edu

Division/Organization Endocrinology
Types of Samples Serum and plasma samples from obese normotensive diabetics treated with oral antihyperglycemic agents.
Phenotypic/Genotypic Data Available Obese diabetics without hypertension, on oral antihyperglycemic agents who were admitted to the Grady CIN to undergo a 48 hour intralipid infusion, a 48 hour normal saline infusion and a second 48 hour intralipid infusion after being treated with rosiglitazone or placebo for 6 weeks, on 3 different dates.  Blood pressure, inflammation.
Interest in Collaboration Yes
More Information

Samples from 23 obese normotensive diabetics treated with oral antihyperglycemic agents only who received a 48 hour intralipid infusion (79 serum samples and 22 plasma samples per patient per admission), a 48 hour normal saline infusion (79 serum samples and 22 plasma samples per patient per admission), and a second 48 hour intralipid infusion after being treated with rosiglitazone or placebo (79 serum samples and 22 plasma samples per patient per admission).

Samples from 4 obese, normotensive, nondiabetics who served as controls for this study.  These subjects received the same infusion as the diabetics.

Genotyping and Phenotyping of Subjects

Principal Investigator Ignacio Sanz
Contact Person

In addition to PI, please call Jennifer Scantlin: 404-712-2943, jennifer.scantlin@emory.edu

Division/Organization Rheumatology / Lowance Center
Types of Samples Blood
Phenotypic/Genotypic Data Available Genotype data, with an emphasis on identifying autoimmune diseases susceptible genes.
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to Emory under approved MTAs.

 

The Grady Trauma Project

Principal Investigator Kerry Ressler, MD, PhD
Contact Person

Kerry Ressler, MD, PhD or call 404-727-7739

Types of Samples Salivary DNA / GWAS sampling on 5000 subjects, and Whole Blood, Plasma, Serum and Urine on 800 of those subjects.
Associated Phenotypic / Genotypic Data Psychological (self-report and clinical interview) data on 5000 subjects:  demographic, geocoding, stress, trauma, depression, PTSD, and other risk as well as resilience phenotypes are available.  Physiology (HR, galvanic skin response, acoustic startle response, measures of fear and extinction) on 500 subjects.  Neuroimaging data (fMRI resting state, task dependent, and structural) on >100 subjects.
Interest in Collaboration Potentially, depending on the circumstances and questions.
More Information The Sample represents  a cross-sectional, epidemiological sampling of subjects (18-65yo; 60% females; 90% African-American) from inner-city Atlanta attending Grady Memorial Hospital outpatient clinics.  Although the focus of the study is civilian Posttraumatic Stress Disorder (PTSD), demographic, geocoding, stress, trauma, depression, PTSD, and other risk as well as resilience phenotypes are available.

Up to 40% of the variance determining who develops Posttraumatic Stress Disorder following a severe trauma is genetically heritable. By focusing on genes that differentially associate with presence or absence of PTSD in a similarly highly- traumatized population, we plan to prioritize genes with a high likelihood of critical involvement in the etiology of PTSD. Identifying the genetic pathways involved with PTSD, combined with our increasing understanding of the neural circuitry of fear and stress-dysregulation, will lead to an improved neurobiological understanding, enhanced prevention, and improved treatment of this debilitating and prevalent syndrome.

HIV Specimen Repository of the Center for AIDS Research Clinical Research Core

Principal Investigator Wendy Armstrong
Contact Person

Cameron Tran (404) 616-9330 or t.cameron.tran@emory.edu

Division/Organization Infectious Diseases
Types of Samples

PBMCs, cell pellets, plasma, sera

Stage of Infection: HIV uninfected, Acute HIV infection, Recent HIV infection, Long-term non-progressor
Virologic Control: Elite controller, Viremic controller
Co-infections: Acute Hepatitis B, Acute Hepatitis C
Treatment Status: Anti-retroviral treatment naïve, Anti-retroviral treatment naïve, beginning therapy (with samples collected longitudinally while on therapy)

Phenotypic/Genotypic Data Available Standard data collected are demographic, viral load, CD4, ARV treatment regimen; and also have IRB approval to access patient medical records for additional data.
Interest in Collaboration Yes
More Information

Three CFAR@Emory Clinical Research Core sites – the Grady Health System Ponce de Leon Center Infectious Diseases Program (Ponce Clinic), the Emory Healthcare Infectious Disease Clinic at Emory University Hospital Midtown (Midtown Clinic), and the Infectious Disease Clinic of the Atlanta Veteran’s Affairs Medical Center (VA clinic) – collectively treat more than 8,000 patients with HIV.

Biologic samples from selected patients at our Ponce, Midtown and VA clinics, along with samples from healthy volunteers recruited through the Clinical Core's site at the Hope Clinic of the Emory Vaccine Center, are available through the CFAR Clinical Research Database and Linked Specimen Repository.  As part of the NIAID network of CFARs, Emory investigators have access to repositories at academic sites from across the nation.

 

Identifying the Cellular Origin of HIV Broadly Neutralizing Antibodies

Principal Investigator Ignacio Sanz
Contact Person

In addition to PI, please call Jennifer Scantlin: 404-712-2943, jennifer.scantlin@emory.edu

Division/Organization Rheumatology / Lowance Center
Types of Samples Blood
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to Emory under approved MTAs.

 

Immune Assay Development

Principal Investigator Ignacio Sanz
Contact Person

In addition to PI, please call Jennifer Scantlin: 404-712-2943, jennifer.scantlin@emory.edu

Division/Organization Rheumatology / Lowance Center
Types of Samples Blood, synovial fluid, nasal polyps, tonsils
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to Emory under approved MTAs.

 

Immunologic Cell Marker Study

Principal Investigator Ignacio Sanz
Contact Person

In addition to PI, please call Jennifer Scantlin: 404-712-2943, jennifer.scantlin@emory.edu

Division/Organization Rheumatology / Lowance Center
Types of Samples Blood, bone marrow, tonsil
Phenotypic/Genotypic Data Available T-cell phenotype
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to Emory under approved MTAs.

Intensive Insulin Therapy in Patients Undergoing Coronary Artery Bypass Grafting

Principal Investigator Guillermo Umpierrez
Contact Person

Saumeth Cardona, scardon@emory.edu; Phone: 404-489-9239

Division/Organization Endocrinology
Types of Samples 3 x 0.5 ml serum aliquots and 3 x 0.5 ml plasma aliquots taken at each timepoint previously described.
Phenotypic/Genotypic Data Available

Samples are from diabetics (T2DM) and non-diabetic patients that undergo CABG surgery, and develop hyperglycemia (BG>140mg/dL) peri-operative or post/operative in the Intensive Care Unit. Patients are randomized to one of 2 groups (Intensive treatment BG goal: 100-140 mg/dL or Standard treatment BG goal 141-180 mg/dL) in the intensive care unit, managed with CII after transitions to SQ Insulin Therapy all patients BG goal: <140mg/dL

Interest in Collaboration Yes
More Information

326 patient samples.
Timepoints of the study:
• Baseline: Prior to CABG surgery
• Day 3: POD 3
• Day 5: POD 5
• Discharge: If discharge day differs from day 5
• 30 Days follow up: 4 weeks after discharge day
• 90 days follow up: 12 weeks after discharge day.
Blood is collected, spun, and stored in GCRC-EUH and GCRC-EUHM freezers.

 

Ketosis Prone Diabetes Mellitus (KPDM) in African American; Insulin Signaling, Proteonomics and Genomics

Principal Investigator Dawn Smiley
Contact Person

Isabel Anzola 404-616-1104, ianzola@emory.edu

Division/Organization Endocrinology
Types of Samples Serum aliquots from the modified oral glucose tolerance test (-5min - 120min), muscle biopsies
Phenotypic/Genotypic Data Available

African American patients, BMI more than 28, between 18-65 years.

Interest in Collaboration Yes
More Information

Samples are from 34 patients enrolled in the KPDM study who are active.  Muscle biopsy samples collected one week after the onset of KPDM (Acute Hyperglycemia or DKA) and one week after weaning off insulin (takes around 8-12 weeks the weaning off process).  At that moment patients receive a modified oral glucose tolerance test (mOGTT), which is repeated after 3 months, and then every 6 months until a total of 7 mOGTTs are collected.  Samples are stored in GCRC-Grady freezers.

 

Measurement of Immunological responses from Human blood of healthy volunteers

Principal Investigator Ignacio Sanz
Contact Person

In addition to PI, please call Jennifer Scantlin: 404-712-2943, jennifer.scantlin@emory.edu

Division/Organization Rheumatology / Lowance Center
Types of Samples Blood
Phenotypic/Genotypic Data Available Genotype data, with an emphasis on identifying autoimmune diseases susceptible genes.
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to Emory under approved MTAs.

Mechanisms Underlying Beta-cell failure In Obese African-Americans With History Of Hyperglycemic Crises

Principal Investigator Guillermo Umpierrez
Contact Person

Gonzalo Robalino; (404) 616 3719; garobal@emory.edu

Division/Organization Endocrinology
Types of Samples Serum and plasma samples from diabetic patients admitted with new onset diabetes and obese subjects without diabetes taken following dextrose or lipid infusions.
Phenotypic/Genotypic Data Available

Obese patients diagnosed with new onset diabetes who were admitted to the hospital either with DKA or severe hyperglycemia (BG > 400 on admission).

Interest in Collaboration Yes
More Information

Samples from 13 diabetic patients admitted with new onset diabetes (new onset DKA or new onset severe hyperglycemia);  subjects received 20 hour dextrose infusions (75 serum samples  and 150 plasma samples per subject drawn every hour during the infusion) and 48 hour Intralipid infusions (59 serum samples and 118 plasma samples per subject drawn every 2 hours during the infusion).

Samples from  7 control obese subjects without diabetes who served as controls for the study. These subjects also received the dextrose and the intralipid infusions in the same fashion as the diabetics.

Subjects were treated with insulin to maximize blood glucose control and were succesfully weaned off of insulin and remained in normoglycemia;  after achieving normoglycemia, subjects were admitted to the Grady CIN to undergo dextrose infusions and lipid infusions on separate days to determine if these infusions would cause an acute B-cell dysfunction in a controlled setting

 

Nasal Polyps and B Cells

Principal Investigator Ignacio Sanz
Contact Person

In addition to PI, please call Jennifer Scantlin: 404-712-2943, jennifer.scantlin@emory.edu

Division/Organization Rheumatology / Lowance Center
Types of Samples Blood, nasal polyps
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to Emory under approved MTAs.


PO-1 Clinical Core: B Cells in Health and Disease

Principal Investigator Ignacio Sanz
Contact Person

In addition to PI, please call Jennifer Scantlin: 404-712-2943, jennifer.scantlin@emory.edu

Division/Organization Rheumatology / Lowance Center
Types of Samples Blood and Synovial fluid
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to Emory under approved MTAs.

 

Predictive Health Institute Center for Health Discovery and Well Being Cohort

Principal Investigator Ken Brigham
Contact Person

Jane Clark, CHDWB@emory.edu

Division/Organization Predictive Health Institute Center for Health Discovery and Well Being
Types of Samples

Serial samples of serum, urine, DNA, RNA

Phenotypic/Genotypic Data Available Extensive questionnaire data, physical and biochemical measurements (2000 data points), collected serially with wet samples
Interest in Collaboration Yes

 

Program for Biodefense of Immunocompromised populations

Principal Investigator Ignacio Sanz
Contact Person

In addition to PI, please call Jennifer Scantlin: 404-712-2943, jennifer.scantlin@emory.edu

Division/Organization Rheumatology / Lowance Center
Types of Samples Blood, bone marrow, tonsil biopsies
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to Emory under approved MTAs.

 

Schizophrenia

Principal Investigator Erica Duncan
Contact Person

Erica Duncan, MD, 404-321-6111 ext 7532;Erica.duncan@va.gov

Division/Organization Psychiatry
Types of Samples Frozen whole blood, extracted DNA
Phenotypic/Genotypic Data Available Results of structured diagnostic interviews, demographic information, smoking status questionnaire, personality testing (for non-schizophrenia subjects), symptom ratings (schizophrenia subjects), demographics, medical and psychiatric medications, cognitive testing, results of acoustic startle and prepulse inhibition of acoustic startle, results of reward paradigm.
Interest in Collaboration Yes
More Information Samples were collected from schizophrenia subjects and their family member as well as from healthy controls and their family members.

 

Sepsis/ARDS Registry

Principal Investigator Greg Martin
Contact Person

Paula Massey (pmassey@emory.edu)

Division/Organization Pulmonary
Types of Samples Plasma samples collected at a single early (within 72 hours of developing disease) timepoint, Bronchoalveolar lavage is available in select patients who were enrolled into a subsequent trial.
Phenotypic/Genotypic Data Available Demographics, information during index hospitalization with disease including physiological and laboratory parameters and clinical outcomes (length of hospital stay, vital status at discharge)
Interest in Collaboration Yes
More Information Prospective registry of severe sepsis and acute lung injury/acute respiratory distress syndrome patients in the Emory system, which serves as a foundation for subsequent enrollment into clinical trials.

Sjogren's biomarkers

Principal Investigator Ignacio Sanz
Contact Person

In addition to PI, please call Jennifer Scantlin: 404-712-2943, jennifer.scantlin@emory.edu

Division/Organization Rheumatology / Lowance Center
Types of Samples Blood, saliva, salivary gland/lip biopsies
Phenotypic/Genotypic Data Available Gene expression profiles from different B cell subsets by microarray
Interest in Collaboration Yes
More Information Samples were collected at the University of Rochester and transferred to Emory under approved MTAs.

 

Tissue bank for hematological disorders

Principal Investigator Hanna Jean Khoury
Contact Person

Susan Sunay, MPH
Research Project Coordinator, Sr.
404-778-5387; ssunay2@emory.edu

Division/Organization Winship Cancer Institute
Types of Samples Buccal wash, blood, bone marrow, cerebrospinal fluid, lymph nodes
Phenotypic/Genotypic Data Available All samples are collected while patient is having diagnostic testing done, so we have associated clinical information.
Interest in Collaboration Yes – interested collaborators should submit a proposal through link at bottom of Hematology website: http://winshipcancer.emory.edu/leukemia/WinshipContentPage.aspx?nd=654
More Information Germ line and somatic DNA, RNA, or abnormal cells in blood and bone marrow, as well as plasma, serum, lymph nodes, and cerebrospinal fluid (CSF) from patients with hematological disorders collected and banked. Additionally, cryopreserved left over material from the Emory Flow Cytometry laboratory is integrated into this bank. Useful for genomic and proteomic analyses.

 


 

Transplant Center Biorepository

Principal Investigator Aneesh Mehta, MD
Contact Person

Jennifer Robertson, 404-727-2017, jennifer.robertson@emory.edu, or Beth Begley, RN, 404-712-7168, beth.begley@emoryhealthcare.org

Division/Organization Emory Transplant Center
Types of Samples Blood, urine, tissue samples from solid organ transplant recipients and/or patients with end-stage organ disease who are awaiting organ transplant; blood and urine from living kidney donors and healthy controls. Now includes pediatric samples as well.
Phenotypic/Genotypic Data Available Renal diagnoses of rejection, stable function or viremia.
Interest in Collaboration Yes
More Information

Click here for detailed description

RedCap data base in place in which kidney biopsies tracked.  The clinical data from the biopsies are uploaded in RedCap and reviewed by a nephrologists to make a diagnosis which is then associated to the sample set.  

Study Request Form http://survey.emory.edu/fs-etcbiostudyrequest.aspx
Specimen Request Form http://survey.emory.edu/fs-etcbiospecirequest.aspx

 

Weight Gain in Pregnancy Study

Principal Investigator Guillermo Umpierrez
Contact Person

Jessica Marcinkevage, jmarcin@emory.edu

Division/Organization Endocrinology
Types of Samples Serum aliquots from a 5-point 2-h oral glucose tolerance test (0 - 120 min)
Phenotypic/Genotypic Data Available Overweight/obese pregnant Black women at three timepoints: <20 weeks gestation, 24-28 weeks gestation and 6 weeks postpartum.
Interest in Collaboration Yes
More Information Samples are from 57 women enrolled in a weight gain in pregnancy study. Women receive a 2-h oral glucose tolerance test at three timepoints as part of the study: <20 weeks, 24-28 weeks gestation, and 6 weeks postpartum.  Blood is collected at 0 min, 30 min, 60 min, 90 min, and 120 min, spun, and stored in GCRC-Grady freezers.