Renal Concentrating Laboratory

    The Renal Concentrating lab, led by Jeff Sands, MD (Division Director, Renal Medicine), investigates mechanisms for concentrating urine in the inner medulla of the kidney. Our current research projects focus on defining the molecular physiology of urea transporters, since urea transport is a key component in the urine-concentrating mechanism. The ultimate goal of this research is to develop strategies to improve kidney function in patients with nephrogenic diabetes insipidus, a disease that causes frequent urination. These strategies could involve repurposing existing medications to improve patients’ urine-concentrating ability.

    Meet the key researchers in the Renal Concentrating Lab and learn more about their work:

    Jeff Sands Janet Klein Yanhua Wang

    Jeff M. Sands, MD
    Kokko Professor of Medicine & Physiology
    Renal Division Director
    Research Focus Areas

    Janet D. Klein, PhD
    Associate Professor of Medicine & Physiology
    Research Focus Areas

    Yanhua Wang, PhD
    Assistant Professor of Medicine
    Research Focus Areas

    Lab Members

    Lauren Larocque Joseph Ruiz Josephine Liwang
    Lauren LaRocque
    Research Specialist Lead
    Publications
    Joseph Ruiz
    Research Specialist
    Josephine Liwang
    Student Researcher

    Contact Information

    Jeff M. Sands, MD
    Juha P. Kokko Professor of Medicine and Physiology
    Renal Division Director
    Emory University Dept. of Medicine, Renal Division
    1639 Pierce Drive, NE
    WMB Rm 3313
    Atlanta, GA  30322

    Phone: 404-727-2525
    Fax: 404-727-3425
    E-mail: jeff.sands@emory.edu

    Janet D. Klein, PhD
    Associate. Professor of Medicine and Physiology
    Department of Medicine, Renal Division
    WMB Rm 3319B
    1639 Pierce Drive, NE
    Atlanta, GA  30322

    Email: janet.klein@emory.edu
    Phone:  404-727-9933

    Yanhua Wang, PhD
    Assistant Professor of Medicine 
    Division of Renal Medicine
    Woodruff Memorial Building (WMB), Room 338F
    1639 Pierce Drive, NE
    Atlanta, GA  30322

    Email: ywang68@emory.edu
    Phone: 404- 712-9538

    Visiting scientists that have trained in the lab

    • Orhan Efe, MD  (Hacettepe University, Turkey)
    • Huiwen Ren, PhD  (Peking University (formerly), currently Tianjin, China)
    • Juan Wang, MD  (Tongji University, Shanghai, China)
    • Ling Chen, MD   (Zhongnan Hospital of Wuhan University, Wuhan, China)
    • Wei Lu, MD   (Xinhua Hospital,  School of Medicine  Shanghai JiaoTong University)
    • Rong Zhou, MD   (Yangpu Hospital Tongji University)
    • Denise Pereira Dos Santos, MD (Brazil)
    • DungUn Kim, MD  (Seoul, Korea)

    Students that have trained in the lab and their later careers

    • Titilayo Ilori (MD Fellow, Instructor, Emory U., Renal Division)
    • Ray Keller (ASN research scholar, Medical Student, University of New England College of Osteopathic Medicine)
    • Dyanna Fountain (visiting medical student, Morehouse School of Medicine)
    • Joseph Ruiz  (Undergraduate research, research specialist, Emory)
    • Katherine Pohl (SURE student, research specialist)
    • Randy Gertner (MD Fellow, Private Practice)
    • Benjamin Nanes  (Undergraduate research, MD/PhD Resident UT Southwestern)
    • Monica Hokanson  (Undergraduate research, MD specializing in Obstretrics)
    • Barbara Gafford-Hampton, PhD (APS Teacher Research Experience, Science Teacher)
    • Nathan Blessing (Undergraduate research, Honors Thesis, MD specializing in Opthamology)
    • Lorien (Sunhye) Kim (Step-up Student-NIH; Medical Student, Mercer University)
    • Raed Bou Matar (Medical fellow, Asst. Professor and Pediatric Nephrologist, Cleveland Clinic)
    • Priya Datta (Undergraduate research, Client analyst)

    Research opportunities for undergraduate students

    Dr. Sands is the PI of an NIH grant that supports summer research experiences for undergraduate students interested in research in Kidney Physiology – the SUPERR.

    Emory's Division of Renal Medicine offers the Summer Undergraduate Program in Emory Renal Research (SUPERR) for undergraduate students looking to pursue a career in renal medicine research.  The SUPERR program provides a research and didactic experience in the study of kidney, urology, and hematologic diseases among undergraduate students. Following a national recruitment, selected students participate in a 12-week didactic and laboratory or clinical research based experiential program at Emory, culminating with participation in the NIDDK (National Institute of Diabetes and Digestive and Kidney Diseases) sponsored Summer Student Research Symposium at a location in the U.S.

    SUPERR students are:

    • Mentored by research and/or clinical faculty during the entire 11 week program
    • Provided with hands-on training in established research laboratories
    • Provided with classroom training in ethical conduct of research
    • Provided didactic training including journal club and related seminars and training opportunities
    • Provided a forum for presentation of scientific findings

    For more information about the Summer Undergraduate Program in Emory Renal Research, click here.

    If you are a student who may be interested in securing a summer research position, here are additional possible options to secure undergraduate research support: