Research

The Emory University Division of Infectious Diseases is proud of our outstanding accomplishments in a broad spectrum of research, including basic, translational, clinical, and epidemiologic sciences. The Division of Infectious Diseases currently garners more than $30 million in research funding per year, more than any other division in the Emory University Department of Medicine.

Infectious Diseases faculty collaborate actively with other top-rated local and regional programs, including the Emory Vaccine Center, the Emory Department of Microbiology and Immunology, the Emory Rollins School of Public Health, and the Centers for Disease Control and Prevention (CDC), in addition to numerous centers in the United States and abroad.

You can view ongoing trials in Infectious Diseases by visiting Emory Department of Medicine Research clinical trials or by visiting clinicaltrials.gov and searching for Emory and keyword.

Basic Science Research Opportunities

Basic scientific research within the Emory University Division of Infectious Diseases focuses on:

  • Mechanisms and control of antibiotic resistance
  • Treatment of hospital-acquired infections, such as Clostridium difficile (C. difficile)
  • Pathogenesis of infectious diseases, such as bacterial meningitis
  • Basic and translational research in HIV
  • Immunology of host defenses and vaccine development

Major areas of investigation of bacterial pathogens include:

  • Analysis of virulence mechanisms of invasive bacterial pathogens
  • The role of endogenous bacterial CRISPR/Cas9 systems in host immune evasion and targeted DNA editing
  • Genomics of bacterial virulence and antibiotic resistance; study of the microbiome
  • Studies of the molecular mechanisms of antibiotic resistance
  • Research into the role of transposable elements and repetitive nucleotide sequences in microbial pathogenesis and agents associated with bioterrorism
  • Metagenomics of pathogens for basic and clinical research

The Division of Infectious Diseases participates in graduate programs and research in microbiology and molecular genetics, immunology and molecular pathogenesis, as well as population biology, ecology, and evolution.

Additional opportunities are available for basic science research in:

  • Toxin-mediated infections
  • Intracellular pathogens
  • Influenza
  • Hemorrhagic fever viruses
  • Zoonotic pathogens
  • Parasites and fungi
  • Population biology
  • Genomics and metagenomics

Emory Vaccine Center and Emory Hope Clinic

The Emory Vaccine Center receives more than $24 million in sponsored research funding. Primary program areas in basic science and translational research currently include HIV/AIDS, tuberculosis, malaria, Hepatitis C virus (HCV), cytomegalovirus, gamma-herpes viruses, influenza and DNA and protein-conjugate vaccines.

The Hope Clinic, a unit of the Emory Vaccine Center directed by Mark Mulligan, MD, conducts clinical research, vaccine trials and critical research on vaccine policies. A number of additional opportunities for basic scientific research are available in the Graduate Divisions of Microbiology and Immunology and through the Centers for Disease Control.

Clinical and Diagnostic Microbiology

Emory University Hospital and Grady Memorial Hospital have outstanding resources in diagnostic and clinical microbiology.

Areas of focus include:

  • Development and assessment of diagnostic tools based on nucleic acid detection
  • Optimization of laboratory procedures for diagnosis of mycobacterial infections
  • Assessment of the accuracy of automated systems for detection of antimicrobial resistance

Clinical/Translational Research Opportunities and Global Health

Major areas of focus for clinical/translational research in infectious diseases include:

  • HIV/AIDS; access to and retention in care
  • Emerging Infections Program
  • Sexually transmitted infections
  • C. difficile infections; prevention and treatment modalities
  • Tuberculosis
  • Vaccine research
  • Healthcare epidemiology and healthcare infections
  • Transplant Infectious Diseases
  • Emerging infectious diseases
  • Global health
  • Bioterrorism

Clinical research training opportunities are enhanced by the presence of Clinical Interaction Sites at the Emory-affiliated hospitals.

In addition, opportunities for clinical and translational research training are enhanced by the presence of the NIH-funded CTSA award (Atlanta Clinical and Translational Science Institute, or ACTSI) which was awarded to Emory University in collaboration with Morehouse School of Medicine and the Georgia Institute of Technology. A major component of the ACTSI is the Research Education, Training and Career Development program, which includes the Master of Science in Clinical Research (MSCR).