Basic Science Research

Within the cardiology division at Emory, we are fortunate to have assembled a very interactive and productive team of cardiovascular investigators. In the basic research laboratories, we have made numerous contributions in vascular biology, particularly related to the areas of atherosclerosis and hypertension, as well the biology of oxygen radicals and their role in both normal vessel function and vascular disease. For more than a decade, our research team has been at the forefront of investigating how vascular cells produce reactive oxygen species and how these molecules affect vascular tone, growth, lesion formation and remodeling. While our basic research has largely focused on vascular biology, we have strong programs in ion channel and cardiac myocyte research. This program encompasses a broad range of methodologies, including molecular biology, genomics, bioinformatics, cell biology, stem cell research and physiology.

Our basic research program also includes studies of human physiology, and in particular examination of endothelial function in human subjects with a variety of diseases. Studies from our division center on how lipid-lowering affects endothelial function, how hypertension alters vascular function and how plasma markers of disease correlate with endothelial function.

Our successful basic investigators are well funded. All have at least one NIH or AHA grant, and we have the equivalent of three NIH program project grants to support basic research in vascular biology. Other sources of funding include the American Heart Association, the Veterans Administration Hospital, pharmaceutical companies and philanthropic support.

Go to the Faculty page to see more details about specific research topics.