Kathy Griendling PhD

R. Wayne Alexander Professor of Medicine/Vice Chair for Research

Division of Cardiology

Faculty Development/Associate Dean for Faculty Affairs

Division of Cardiology

Phone: 404-727-3364

Fax: 404-727-3585

Email: kgriend@emory.edu

Additional Contact Information

Additional Websites

Biography

Dr. Kathy Griendling received her PhD in Cardiovascular Physiology from Johns Hopkins University in 1982, and performed her post-doctoral training with Dr. Robert Cox at the University of Pennsylvania and Dr. R. Wayne Alexander at Harvard University.  She is currently a Professor of Medicine in the Cardiology Division of Emory University, and a Fellow of the American Heart Association.  She serves as an Associate Editor for Circulation Research and is one of the Executive Editors of Antioxidants and Redox Signaling.  She is Vice Chair for Research and Faculty Development in the Department of Medicine and Assistant Dean for Faculty Development in the School of Medicine.

Dr. Griending’s research is focused on the role of NADPH oxidases (Nox) in vascular biology and disease. Her laboratory uses molecular techniques to study the subunit structure of Nox enzymes, their downstream targets and their role in physiology and pathophysiology.  She has a particular interest in how reactive oxygen species (ROS) derived from these enzymes regulate the signaling pathways leading to smooth muscle proliferation, migration and differentiation.  Using transgenic and knockout mouse models, they have demonstrated a role for the NADPH oxidases in hypertension, collateral formation, vessel contraction and restenosis.   Ongoing research is focused on Poldip2, a p22phox binding protein that regulates Nox4 activity and plays major roles in cell cycle progression, 

Link to Griendling research laboratory website

Dr. Griendling has trained 46 post-doctoral fellows and PhD students, many of whom have successful academic careers.  She is a member of the graduate faculty in Molecular and Systems Pharmacology.

Research

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